EMD-61596
Cryo-EM structure of HSV-2 gB and FAB 16F9 complex
EMD-61596
Single-particle2.18 Å
Deposition: 20/09/2024Map released: 24/09/2025
Last modified: 14/01/2026
Sample Organism:
Human herpesvirus 2,
Mus musculus
Sample: HSV-2 gB and FAB 16F9 complex
Fitted models: 9jmb
Deposition Authors: Li Y
,
Zheng Q ,
Li S ,
Wu Y,
Li S
Sample: HSV-2 gB and FAB 16F9 complex
Fitted models: 9jmb
Deposition Authors: Li Y
,
Zheng Q ,
Li S ,
Wu Y,
Li S
A broadly neutralizing antibody confers cross-genus protection against alphaherpesviruses by inhibiting gB-mediated membrane fusion.
Wang G,
Li Y ,
Wu C,
Chen T,
Gui M,
Zeng Y,
Sun H ,
Chen K,
Xi X,
Yang Y,
Jiang Y,
Jiang Y,
Liu L,
Yang C,
Xin J,
Liu C,
Li Y ,
Huo N,
Huang Y,
Lin L,
Yu H ,
Huang C ,
Yuan Q ,
Li S ,
Tian K,
Zheng Q ,
Xia N ,
Chen Y
(2025) Nat Commun , 16 , 11144 - 11144
,
Wu C,
Chen T,
Gui M,
Zeng Y,
Sun H ,
Chen K,
Xi X,
Yang Y,
Jiang Y,
Jiang Y,
Liu L,
Yang C,
Xin J,
Liu C,
Li Y ,
Huo N,
Huang Y,
Lin L,
Yu H ,
Huang C ,
Yuan Q ,
Li S ,
Tian K,
Zheng Q ,
Xia N ,
Chen Y
(2025) Nat Commun , 16 , 11144 - 11144
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