EMD-61438

Single-particle
2.67 Å
EMD-61438
3D View Gallery
Deposition: 05/09/2024
Map released: 10/09/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61438

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9jfs summary report (pdf.gz) Map-9jfs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of Cas12p-TrxA-guide RNA-target DNA complex(29nt TS and 11nt NTS)

EMD-61438

Single-particle
2.67 Å
EMD-61438
3D View Gallery
Deposition: 05/09/2024
Map released: 10/09/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: unidentified, synthetic construct, Escherichia coli BL21(DE3)
Sample: complex of Cas12p-TrxA-gRNA-target DNA(29-nt TS and 11-nt NTS)
Fitted models: 9jfs

Deposition Authors: Wang ZP, Wang YJ, Ji QJ
Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA.
Wang Z , Wang Y, Gao H, Dai J, Tang N, Wang Y, Ji Q
(2026) Nat Microbiol , 11 , 81 - 93
PUBMED: 41492065
DOI: doi:10.1038/s41564-025-02224-z
ISSN: 2058-5276