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EMD-61167

Single-particle
3.55 Å
EMD-61167
3D View Gallery
Deposition: 15/08/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61167
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9j66 summary report (pdf.gz) Map and 9j66 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment CAV-C65 (local refinement)

EMD-61167

Single-particle
3.55 Å
EMD-61167
3D View Gallery
Deposition: 15/08/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: complex of the SARS-CoV-2 S 6P trimer with the human neutralizing antibody Fab fragment CAV-C65
Fitted models: 9j66

Deposition Authors: Jing X, Chen Y, Gong P
IgA class switching enhances neutralizing potency against SARS-CoV-2 by increased antibody hinge flexibility.
Xu M, Zhang Z, Sun Y, Mai H, Liu S, Liu S, Lv K, Yu F, Wang Y, Yue X, Zhang J, Cai X, Zhao R, Lu H, Liu L, Luo H, Zhao H, Wang Y, Gong P, Chen S, Jing X, Zhao J, Chen YQ
(2025) Antiviral Res , 235 , 106082 - 106082
PUBMED: 39828085
DOI: doi:10.1016/j.antiviral.2025.106082
ISSN: 0166-3542
ASTM: ARSRDR