EMD-61134

Helical reconstruction
2.49 Å
EMD-61134
3D View Gallery
Deposition: 09/08/2024
Map released: 13/08/2025
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61134

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9j4f summary report (pdf.gz) Map-9j4f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of P25alpha full-length A119V fibril

EMD-61134

Helical reconstruction
2.49 Å
EMD-61134
3D View Gallery
Deposition: 09/08/2024
Map released: 13/08/2025
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of P25alpha core fibril
Fitted models: 9j4f

Deposition Authors: Xia WC, Sun YP, Huang CA, Liu C
TPPP/p25 amyloid seeding activity as a specific biomarker for multiple system atrophy.
Zeng S, Zhang S, Zhang S, Fan Y, Xia W, Chen F, Huang C, Lv S, Lu J, Sun Y, Liu K, Li Y, Zhang Y, Wang J, Liu C, Li D
(2026) Cell , 189 , 4724
PUBMED: 42190663
DOI: doi:10.1016/j.cell.2026.04.050
ISSN: 1097-4172
Grant Support: