Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-60930

Single-particle
3.22 Å
EMD-60930
3D View Gallery
Deposition: 24/07/2024
Map released: 13/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60930
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ivm summary report (pdf.gz) Map and 9ivm FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex in the presence of LSN3318839

EMD-60930

Single-particle
3.22 Å
EMD-60930
3D View Gallery
Deposition: 24/07/2024
Map released: 13/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex in the presence of LSN3318839
Fitted models: 9ivm

Deposition Authors: Li J, Li G, Mai Y, Liu X, Yang D , Zhou Q , Wang M-W
Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839.
Li J, Li G, Mai Y, Liu X, Yang D , Zhou Q , Wang MW
(2024) Acta Pharm Sin B , 14 , 5069 - 5073
PUBMED: 39664415
DOI: doi:10.1016/j.apsb.2024.09.002
ISSN: 2211-3835