EMD-60921

Single-particle
3.5 Å
EMD-60921
3D View Gallery
Deposition: 23/07/2024
Map released: 19/03/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60921

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9iv8 summary report (pdf.gz) Map-9iv8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human NCX1 in PIP2 diC8 bound state

EMD-60921

Single-particle
3.5 Å
EMD-60921
3D View Gallery
Deposition: 23/07/2024
Map released: 19/03/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human cardiac sodium calcium exchanger NCX1
Fitted models: 9iv8

Deposition Authors: Xue J , Jiang Y
Structural mechanisms of PIP 2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1.
Xue J , Zeng W, John S , Attiq N, Ottolia M , Jiang Y
(2025) eLife , 14
PUBMED: 40433952
DOI: doi:10.7554/eLife.105396
ISSN: 2050-084X