EMD-60797

Single-particle
3.37 Å
EMD-60797
3D View Gallery
Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60797

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9iqx summary report (pdf.gz) Map-9iqx FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human TRPV4-RhoA in complex with AH001

EMD-60797

Single-particle
3.37 Å
EMD-60797
3D View Gallery
Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of the human TRPV4-RhoA in complex with AH001
Fitted models: 9iqx

Deposition Authors: Yuan Z , Ruan SS, Li SL
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis.
Wang J , Yuan Z , Yu N, Jiao Q, Zhou H, Liao W, Shan J, Ruan S, Zhao Y , Mo Y, Qi L, Li T, Fu J, Ke B , Xu Y , Qian X , Zhang J , Zhao Z, Li S, Wang R, Li H
(2025) Circulation , 152 , 519 - 536
PUBMED: 40518994
DOI: doi:10.1161/CIRCULATIONAHA.124.071884
ISSN: 1524-4539