EMD-60744

Single-particle
3.46 Å
EMD-60744
3D View Gallery
Deposition: 09/07/2024
Map released: 09/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60744

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9iol summary report (pdf.gz) Map-9iol FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the complex of DNA, Ku70/80, and laXLF.

EMD-60744

Single-particle
3.46 Å
EMD-60744
3D View Gallery
Deposition: 09/07/2024
Map released: 09/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The complex of DNA, Ku70/80, and laXLF
Fitted models: 9iol

Deposition Authors: Liang S
Lactylation of XLF promotes non-homologous end-joining repair and chemoresistance in cancer.
Jin M, Huang B, Yang X, Wang S, Wu J, He Y, Ding X, Wang X, Wang Z, Yang J, Li R, Zhou X, Wang Q, Li Y, Li L, Zheng W, Zeng Z, Zhao C, Liu J, Zhu Q, Kang Z, Li K, Liang S , Chen Y, Yuan J
(2025) Mol Cell , 85 , 2654 - 2672.e7
PUBMED: 40680721
DOI: doi:10.1016/j.molcel.2025.06.019
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: