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EMD-60647

Single-particle
2.61 Å
EMD-60647
3D View Gallery
Deposition: 26/06/2024
Map released: 04/09/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60647
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ik1 summary report (pdf.gz) Map and 9ik1 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human P2X3 receptor-compound 26a complex

EMD-60647

Single-particle
2.61 Å
EMD-60647
3D View Gallery
Deposition: 26/06/2024
Map released: 04/09/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human P2X3 receptor-compound 26a complex
Fitted models: 9ik1

Deposition Authors: Kim S, Kim GR, Kim YO, Han X, Nagel J, Kim J, Song DI, Muller CE , Yoon MH, Jin MS, Kim YC
Discovery of Triazolopyrimidine Derivatives as Selective P2X3 Receptor Antagonists Binding to an Unprecedented Allosteric Site as Evidenced by Cryo-Electron Microscopy.
Kim GR, Kim S, Kim YO, Han X, Nagel J, Kim J, Song DI, Muller CE , Yoon MH, Jin MS, Kim YC
(2024) J Med Chem , 67 , 14443 - 14465
PUBMED: 39102524
DOI: doi:10.1021/acs.jmedchem.4c01214
ISSN: 0022-2623
ASTM: JMCMAR