EMD-60281
CD73 bound with HB0045
EMD-60281
Single-particle3.06 Å
Deposition: 28/05/2024Map released: 05/02/2025
Last modified: 19/02/2025
Sample Organism:
Homo sapiens
Sample: CD73 complexed with HB0017 antibody coaktail
Fitted models: 8znz
Deposition Authors: Xu J, Wan L
,
He Y
Sample: CD73 complexed with HB0017 antibody coaktail
Fitted models: 8znz
Deposition Authors: Xu J, Wan L
,
He Y
An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control.
Xu JG,
Chen S,
He Y,
Zhu X ,
Wang Y,
Ye Z,
Zhou JC,
Wu X,
Zhang L,
Ren X ,
Jia H,
Yu H,
Wei X,
Feng Y,
Chen X,
Cui X,
Pan X,
Wang S,
Xia S,
Shang H,
Pu Y,
Xu W,
Li H ,
Chen Q,
Chen Z ,
Wang M,
Yan X,
Shi H,
Li M,
Xia Y,
Bellelli R ,
Dong S,
He J ,
Huang J ,
Cai CL,
Zhu X ,
Zhan Y ,
Wan L
(2024) Nat Commun , 15 , 10872 - 10872
,
Wang Y,
Ye Z,
Zhou JC,
Wu X,
Zhang L,
Ren X ,
Jia H,
Yu H,
Wei X,
Feng Y,
Chen X,
Cui X,
Pan X,
Wang S,
Xia S,
Shang H,
Pu Y,
Xu W,
Li H ,
Chen Q,
Chen Z ,
Wang M,
Yan X,
Shi H,
Li M,
Xia Y,
Bellelli R ,
Dong S,
He J ,
Huang J ,
Cai CL,
Zhu X ,
Zhan Y ,
Wan L
(2024) Nat Commun , 15 , 10872 - 10872
Grant Support: