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EMD-60281
CD73 bound with HB0045
EMD-60281
Single-particle3.06 Å
Deposition: 28/05/2024Map released: 05/02/2025
Last modified: 19/02/2025
Sample Organism:
Homo sapiens
Sample: CD73 complexed with HB0017 antibody coaktail
Fitted models: 8znz
Deposition Authors: Xu J, Wan L
,
He Y
Sample: CD73 complexed with HB0017 antibody coaktail
Fitted models: 8znz
Deposition Authors: Xu J, Wan L
,
He Y
An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control.
Xu JG,
Chen S,
He Y,
Zhu X ,
Wang Y,
Ye Z,
Zhou JC,
Wu X,
Zhang L,
Ren X,
Jia H,
Yu H,
Wei X,
Feng Y,
Chen X,
Cui X,
Pan X,
Wang S,
Xia S,
Shang H,
Pu Y,
Xu W,
Li H ,
Chen Q,
Chen Z ,
Wang M,
Yan X,
Shi H,
Li M,
Xia Y,
Bellelli R ,
Dong S,
He J ,
Huang J ,
Cai CL,
Zhu X ,
Zhan Y ,
Wan L
(2024) Nat Commun , 15 , 10872 - 10872
,
Wang Y,
Ye Z,
Zhou JC,
Wu X,
Zhang L,
Ren X,
Jia H,
Yu H,
Wei X,
Feng Y,
Chen X,
Cui X,
Pan X,
Wang S,
Xia S,
Shang H,
Pu Y,
Xu W,
Li H ,
Chen Q,
Chen Z ,
Wang M,
Yan X,
Shi H,
Li M,
Xia Y,
Bellelli R ,
Dong S,
He J ,
Huang J ,
Cai CL,
Zhu X ,
Zhan Y ,
Wan L
(2024) Nat Commun , 15 , 10872 - 10872
Grant Support: