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EMD-60107

Single-particle
3.96 Å
EMD-60107 Deposition: 11/05/2024
Map released: 21/08/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60107

SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs

EMD-60107

Single-particle
3.96 Å
EMD-60107 Deposition: 11/05/2024
Map released: 21/08/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2, synthetic construct
Sample: SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs
Fitted models: 8zhl

Deposition Authors: Yan Q , Gao X , Liu B, Hou R, He P, Li Z, Chen Q, Wang J, He J , Chen L , Zhao J , Xiong X
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants.
Yan Q , Gao X , Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J , Chen L , Zhao J , Xiong X
(2024) Nat Commun , 15 , 7585 - 7585
PUBMED: 39217172
DOI: doi:10.1038/s41467-024-51770-3
ISSN: 2041-1723