EMD-59642

Helical reconstruction
2.9 Å
EMD-59642
3D View Gallery
Deposition: 27/08/2026
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-59642

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-33wp summary report (pdf.gz) Map-33wp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Single protofilament with the Alzheimer tau fold and the V337M mutation from seeded primary murine neurons

EMD-59642

Helical reconstruction
2.9 Å
EMD-59642
3D View Gallery
Deposition: 27/08/2026
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Single protofilament with the Alzheimer tau fold and the V337M mutation from seeded primary murine neurons
Fitted models: 33wp

Deposition Authors: Huang M, Scheres SHW , Goedert M
Templated paired helical filament formation and tau fold-dependent inclusion morphologies in primary neurons.
Huang M, Lovestam S, Cheam KAX, Ghetti B, McEwan WA, Scheres SHW , Goedert M
(2026) bioRxiv
PUBMED: 42926395
DOI: doi:10.64898/2026.09.30.755038
ISSN: 2692-8205
Grant Support: