EMD-58555

Single-particle
3.07 Å
EMD-58555
3D View Gallery
Deposition: 12/06/2026
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-58555
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 31mr summary report (pdf.gz) Map and 31mr FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes complexed with an anti-PA-domain monoclonal antibody

EMD-58555

Single-particle
3.07 Å
EMD-58555
3D View Gallery
Deposition: 12/06/2026
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Streptococcus pyogenes, Mus musculus
Sample: SpyCEP complexed with 3F2G10
Fitted models: 31mr

Deposition Authors: Lau RJ, Barritt JD, Wu GHY, Huemer CB, Matthews S
SpyCEP dismantles neutrophil immunity via disorder-driven chemokine remodeling and GAG targeting
Lau RJ, Giblin SP, Sugar A, Di Maio A, Tassini G, Huse K, Chorev D, Chen Y, Wu GHY, Huemer CB, Kim SY, Matthews J, Muloud B, Chen L, McKenna S, Xu Y, Massai L, Muzzi C, Ferhati X, Necchi F, Moriel DG, Feizi T, Liu Y, Pease JE, Sriskandan S, Matthews S
(2026) PNAS
Grant Support: