EMD-56909

Single-particle
3.23 Å
EMD-56909
3D View Gallery
Deposition: 24/02/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56909

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focus refined map of ZMYND19 bound to discoidin domain of substrate receptor MKLN1

EMD-56909

Single-particle
3.23 Å
EMD-56909
3D View Gallery
Deposition: 24/02/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Focus refined map of ZMYND19 bound to discoidin domain of substrate receptor MKLN1

Deposition Authors: Sepic S, Chrustowicz J , Du J, Schulman BA
Multimodal substrate recruitment enables CTLH MKLN1 E3 ligase to target acetylated N-, C-, and internal degrons.
Sepic S, Gottemukkala KV, Du J, Maiwald SA, Chrustowicz J , Papadopoulou EC , Stier LJ, von Gronau S, Schulman BA
(2026) Nat Commun , 17
PUBMED: 42892655
DOI: doi:10.1038/s41467-026-78311-4
ISSN: 2041-1723
Grant Support: