EMD-56566

Single-particle
3.91 Å
EMD-56566
3D View Gallery
Deposition: 04/02/2026
Map released: 06/05/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56566

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-28jv summary report (pdf.gz) Map-28jv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human holo-TFIIH-XPC complex bound to bulky lesion-mimic DNA (consensus map)

EMD-56566

Single-particle
3.91 Å
EMD-56566
3D View Gallery
Deposition: 04/02/2026
Map released: 06/05/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human holo-TFIIH, XPC complex, and XPA with biotinylated DNA.
Fitted models: 28jv

Deposition Authors: de Martin Garrido N, Haste CAF, Feng J, Cronin NB, Greber BJ
Visualization of stepwise derepression of TFIIH in global genome nucleotide excision repair.
de Martin Garrido N, Haste CAF, Feng J, Cronin NB, Greber BJ
(2026) Sci Adv , 12 , eaeb3506 - eaeb3506
PUBMED: 42490432
DOI: doi:10.1126/sciadv.aeb3506
ISSN: 2375-2548