EMD-56551

Single-particle
3.32 Å
EMD-56551
3D View Gallery
Deposition: 03/02/2026
Map released: 06/05/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56551

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-28js summary report (pdf.gz) Map-28js FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the human holo-TFIIH-XPC complex bound to bulky lesion-mimic DNA (composite map)

EMD-56551

Single-particle
3.32 Å
EMD-56551
3D View Gallery
Deposition: 03/02/2026
Map released: 06/05/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human holo-TFIIH, XPC complex, and XPA with biotinylated DNA.
Fitted models: 28js

Deposition Authors: de Martin Garrido N, Haste CAF, Feng J, Cronin NB, Greber BJ
Visualization of stepwise derepression of TFIIH in global genome nucleotide excision repair.
de Martin Garrido N, Haste CAF, Feng J, Cronin NB, Greber BJ
(2026) Sci Adv , 12 , eaeb3506 - eaeb3506
PUBMED: 42490432
DOI: doi:10.1126/sciadv.aeb3506
ISSN: 2375-2548