EMD-56448

Single-particle
4.5 Å
EMD-56448
3D View Gallery
Deposition: 21/01/2026
Map released: 04/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56448

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of mouse Pannexin 1 in complex with a ligand

EMD-56448

Single-particle
4.5 Å
EMD-56448
3D View Gallery
Deposition: 21/01/2026
Map released: 04/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse Pannexin 1 in complex with a ligand

Deposition Authors: Drulyte I
Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles.
Reddavide FV, Toft-Bertelsen TL, Drulyte I , Gutgsell AR, Nguyen D, Bonetti S, Vafia K, Tournillon AS, Heiden S, Grosser D, Iric K, Diez V, MacAulay N, Geschwindner S, Thompson M, Frauenfeld J, Loving R
(2026) Sci Rep
PUBMED: 42298013
DOI: doi:10.1038/s41598-026-58370-9
ISSN: 2045-2322
Grant Support: