EMD-56404

Single-particle
3.3 Å
EMD-56404
3D View Gallery
Deposition: 15/01/2026
Map released: 23/09/2026
Last modified: 23/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56404

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9txl summary report (pdf.gz) Map-9txl FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

ITIH4N:MASP-1cf:12A12 F(ab) 2:1:2 complex (Composite)

EMD-56404

Single-particle
3.3 Å
EMD-56404
3D View Gallery
Deposition: 15/01/2026
Map released: 23/09/2026
Last modified: 23/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Inter-alpha-trypsin inhibitor heavy chain 4 N-terminal fragment in complex with MASP-1cf and 12A12 F(ab) in a 2:1:2 stoichiometry
Fitted models: 9txl

Deposition Authors: Joergensen MH, Andersen GR

The plasma protease inhibitor ITIH4 forms oligomeric complexes and senses broader, proteolytic activity
Joergensen MH, Andersen GR
To Be Published
Grant Support: