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EMD-5624
Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
EMD-5624
Single-particle14.0 Å
Deposition: 27/03/2013Map released: 03/07/2013
Last modified: 03/07/2013
Sample Organism:
Human immunodeficiency virus 1
Sample: Fab fragment of broadly neutralizing antibody PGT122 in complex with HIV-1 SOSIP.664 from BG505
Deposition Authors: Khayat R, Lee JH
,
Julien JP ,
Wilson IA,
Ward AB
Sample: Fab fragment of broadly neutralizing antibody PGT122 in complex with HIV-1 SOSIP.664 from BG505
Deposition Authors: Khayat R, Lee JH
,
Julien JP ,
Wilson IA,
Ward AB
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Julien JP ,
Sok D,
Khayat R,
Lee JH ,
Doores KJ ,
Walker LM,
Ramos A,
Diwanji DC,
Pejchal R,
Cupo A,
Katpally U,
Depetris RS,
Stanfield RL ,
McBride R,
Marozsan AJ,
Paulson JC,
Sanders RW,
Moore JP,
Burton DR,
Poignard P ,
Ward AB,
Wilson IA
(2013) Plos Pathog , 9 , e1003342 - e1003342
,
Sok D,
Khayat R,
Lee JH ,
Doores KJ ,
Walker LM,
Ramos A,
Diwanji DC,
Pejchal R,
Cupo A,
Katpally U,
Depetris RS,
Stanfield RL ,
McBride R,
Marozsan AJ,
Paulson JC,
Sanders RW,
Moore JP,
Burton DR,
Poignard P ,
Ward AB,
Wilson IA
(2013) Plos Pathog , 9 , e1003342 - e1003342