EMD-55800

Single-particle
2.64 Å
EMD-55800 Deposition: 22/11/2025
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55800

Integrin AlphaIIbBeta3 bound to Fab of the anti-HPA-1a antibody 26.4

EMD-55800

Single-particle
2.64 Å
EMD-55800 Deposition: 22/11/2025
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of integrin aIIbb3 ectodomains bound to the Fab 26.4
Fitted models: 9td2

Deposition Authors: de Pereda JM, Stam W, Gragera M, van der Meer F, Chichon FJ, Zarkadas E, van der Schoot E, Vidarsson G, Takagi J, Margadant C

High-resolution cryo-EM structure of integrin aIIbb3 in complex with a disease-causing maternal HPA-1a antibody that blocks integrin activation

Grant Support: