EMD-54982

Helical reconstruction
3.5 Å
EMD-54982
3D View Gallery
Deposition: 02/09/2025
Map released: 11/11/2026
Last modified: 11/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54982

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9sl2 summary report (pdf.gz) Map-9sl2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of proIAPP(1-48)

EMD-54982

Helical reconstruction
3.5 Å
EMD-54982
3D View Gallery
Deposition: 02/09/2025
Map released: 11/11/2026
Last modified: 11/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Pro-human islet amyloid polypeptide
Fitted models: 9sl2

Deposition Authors: Valli D , Maj M
High-resolution structure of proIAPP(1-48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs.
Valli D , Maj M
(2026) Rsc Chem Biol , 7 , 38 - 43
PUBMED: 41210656
DOI: doi:10.1039/d5cb00228a
ISSN: 2633-0679