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EMD-54895

Single-particle
2.85 Å
EMD-54895
3D View Gallery
Deposition: 26/08/2025
Map released: 01/10/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54895
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EMICSS annotations (xml)

Focus map of ternary PROTAC-mediated complex of BRD4-BD1/CRBN/DDB1 and JQ1-AcQ bifunctional degrader

EMD-54895

Single-particle
2.85 Å
EMD-54895
3D View Gallery
Deposition: 26/08/2025
Map released: 01/10/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PROTAC-mediated complex of DDB1 (BPB deletion), CRBN and BRD4 BD1 domain

Deposition Authors: Peter D , Fischer G, Arce Solano S, Kessler D
Enzyme-Activated Sugar-Coated Bifunctional Degraders.
Zhu Q , Fischer G, Cheng SS, Payne NC, Peter D , Mody AC, Arce-Solano S , Shen D , Lin Z, Mazitschek R, Kessler D , Woo CM
(2025) J Am Chem Soc , 147 , 34672 - 34680
PUBMED: 40937862
DOI: doi:10.1021/jacs.5c09843
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: