EMD-54692

Single-particle
2.9 Å
EMD-54692
3D View Gallery
Deposition: 07/08/2025
Map released: 01/10/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54692

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9sao summary report (pdf.gz) Map-9sao FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SARS CoV-2 RdRp S759A mutant in complex with 20-40mer RNA incorporating remdesivir

EMD-54692

Single-particle
2.9 Å
EMD-54692
3D View Gallery
Deposition: 07/08/2025
Map released: 01/10/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS CoV-2 RdRp S759A mutant in complex with 20-40mer RNA incorporating remdesivir
Fitted models: 9sao

Deposition Authors: Oliva MF, Das K
Structural basis for selective remdesivir incorporation by SARS-CoV-2 RNA polymerase, and S759A resistance.
Gordon CJ, Oliva MF, Lee HW, Goovaerts Q, De Wijngaert B, Gotte M, Das K
(2025) bioRxiv
PUBMED: 40950230
DOI: doi:10.1101/2025.09.04.674295
ISSN: 2692-8205
Grant Support: