EMD-54638
Structure of human mitochondrial COX1-translating ribosome nascent chain complex with tRNAs in initial hybrid state (H1)
EMD-54638
Single-particle3.2 Å
Deposition: 04/08/2025Map released: 12/08/2026
Last modified: 12/08/2026
Sample Organism:
Homo sapiens
Sample: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain
Fitted models: 9s7c
Deposition Authors: Schoendorf T, Petrychenko V
,
Kotan I ,
Cruz-Zaragoza LD ,
Dahal D ,
Wang C,
Gal T,
Dennerlein S,
Kramer G ,
Fischer N ,
Rehling P
Sample: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain
Fitted models: 9s7c
Deposition Authors: Schoendorf T, Petrychenko V
,
Kotan I ,
Cruz-Zaragoza LD ,
Dahal D ,
Wang C,
Gal T,
Dennerlein S,
Kramer G ,
Fischer N ,
Rehling P
Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed.
Schondorf T,
Petrychenko V ,
Kotan I ,
Dahal D ,
Napieraj N ,
Cruz-Zaragoza LD ,
Wang C,
Urbach O,
Gall T,
Dennerlein S,
Kramer G ,
Fischer N ,
Rehling P
(2026) Nat Struct Mol Biol , 33 , 853 - 867
,
Kotan I ,
Dahal D ,
Napieraj N ,
Cruz-Zaragoza LD ,
Wang C,
Urbach O,
Gall T,
Dennerlein S,
Kramer G ,
Fischer N ,
Rehling P
(2026) Nat Struct Mol Biol , 33 , 853 - 867
Grant Support:
- European Research Council (ERC): ERCAdG No. 101095062 (European Union)
- German Research Foundation (DFG): SFB1565 (Germany)
- Max Planck Society: (Germany)
- Germanys Excellence Strategy: 390729940 (Germany)