EMD-54624

Single-particle
2.51 Å
EMD-54624
3D View Gallery
Deposition: 31/07/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54624

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Consensus map of CRBN bound to spirocyclic ligand in the open conformation

EMD-54624

Single-particle
2.51 Å
EMD-54624
3D View Gallery
Deposition: 31/07/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of CRL4 E3 adapter-receptor pair DDB1 and CRBN bound to spirocyclic ligand

Deposition Authors: Cowan AD , Rutter ZJ , McAulay K , Ciulli A

Structural and Biophysical Methods for the Assessment of Cereblon Binders for PROTACs
Rutter ZJ , Cowan AD , McAulay K , Ciulli A
To Be Published
Grant Support: