EMD-54532

Single-particle
3.12 Å
EMD-54532
3D View Gallery
Deposition: 24/07/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54532

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9s3f summary report (pdf.gz) Map-9s3f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Gephyrin in complex with Darpin 27F3, revealing linker-E domain interactions

EMD-54532

Single-particle
3.12 Å
EMD-54532
3D View Gallery
Deposition: 24/07/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, synthetic construct
Sample: Gephyrin in complex with Darpin 27F3 partner
Fitted models: 9s3f

Deposition Authors: Ortiz-Lopez D, Hove T, Schindelin H, Boettcher B
Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization.
Ortiz-Lopez D, Hove TT, Huhn C, Camuso S, van Gen Hassend PM, Sander B, Campbell BFN, Tyagarajan SK, Pluckthun A, Specht CG, Maric HM, Bottcher B, Schindelin H
(2026) Nat Commun , 17
PUBMED: 41991925
DOI: doi:10.1038/s41467-026-71771-8
ISSN: 2041-1723