EMD-54357

Single-particle
3.67 Å
EMD-54357
3D View Gallery
Deposition: 10/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54357
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9rx4 summary report (pdf.gz) Map and 9rx4 FULL report (pdf.gz)
EMICSS annotations (xml)

VPS34-CI bound to NRBF2 and RAB1A, primary composite map processed with CryoTEN

EMD-54357

Single-particle
3.67 Å
EMD-54357
3D View Gallery
Deposition: 10/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human VPS34-CI (VPS34/VPS15/BECLIN1/ATG14L) in complex with NRBF2 and RAB1A-GTP (C26S, C126S, Q70L)
Fitted models: 9rx4

Deposition Authors: Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

When VPS34 complexes double down: Two RAB5s for VPS34-CII, two RAB1s for NRBF2-dimerized VPS34-CI
Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL
To Be Published