EMD-54349

Single-particle
3.1 Å
EMD-54349
3D View Gallery
Deposition: 10/07/2025
Map released: 18/03/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54349
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Map B Locally refined interactions of ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO

EMD-54349

Single-particle
3.1 Å
EMD-54349
3D View Gallery
Deposition: 10/07/2025
Map released: 18/03/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CYRANO-AGO2-miR-7 in complex with ZSWIM8-ELONGIN B/C, CUL3

Deposition Authors: Farnung J , Slobodyanyuk E , Bartel DP , Schulman BA

The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation
Farnung J , Slobodyanyuk E , Wang PY, Lin DH, Blodgett LA, Schulman BA , Bartel DP
To Be Published
Grant Support: