EMD-54323

Single-particle
3.54 Å
EMD-54323
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Deposition: 09/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54323
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EMICSS annotations (xml)

VPS34-CI bound to NRBF2 MIT domain (residues 1-79), focused refinement on the VPS34 kinase domain and VPS15 pseudokinase domain

EMD-54323

Single-particle
3.54 Å
EMD-54323
3D View Gallery
Deposition: 09/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human VPS34-CI (VPS34/VPS15/BECLIN1/ATG14L) in complex with NRBF2 MIT domain (residues 1-79)

Deposition Authors: Spokaite S , Ohashi Y , Bourguet M , Dessus AN , Williams RL

When VPS34 complexes double down: Two RAB5s for VPS34-CII, two RAB1s for NRBF2-dimerized VPS34-CI
Spokaite S , Ohashi Y , Dessus AN , Bourguet M , Williams RL
To Be Published