EMD-54316

Single-particle
3.43 Å
EMD-54316
3D View Gallery
Deposition: 09/07/2025
Map released: 03/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54316

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

VPS34-CII (VPS34 199-REIE-202 > 199-AAAA-202 mutant) bound to RAB5A-GTP (Q79L), consensus refinement

EMD-54316

Single-particle
3.43 Å
EMD-54316
3D View Gallery
Deposition: 09/07/2025
Map released: 03/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG) in complex with RAB5A-GTP (C19S, C63S, Q70L)

Deposition Authors: Spokaite S , Ohashi Y , Bourguet M , Dessus AN , Williams RL
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution.
Spokaite S , Ohashi Y , Bourguet M , Dessus AN , Williams RL
(2026) eLife , 15
PUBMED: 42207670
DOI: doi:10.7554/eLife.110040
ISSN: 2050-084X