EMD-54309

Single-particle
3.49 Å
EMD-54309 Deposition: 09/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54309

VPS34-CI bound to NRBF2 and RAB1A, focused refinement on the interface between RAB1A and VPS34

EMD-54309

Single-particle
3.49 Å
EMD-54309 Deposition: 09/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human VPS34-CI (VPS34/VPS15/BECLIN1/ATG14L) in complex with NRBF2 and RAB1A-GTP (Q70L)

Deposition Authors: Spokaite S , Ohashi Y , Bourguet M , Dessus AN , Williams RL

When VPS34 complexes double down: Two RAB5s for VPS34-CII, two RAB1s for NRBF2-dimerized VPS34-CI