EMD-54291

Single-particle
3.0 Å
EMD-54291
3D View Gallery
Deposition: 09/07/2025
Map released: 13/05/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54291

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9rvv summary report (pdf.gz) Map-9rvv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human TRPC5 in complex with (-) englerin A, partial occupancy (2EA:2LIP stoichiometry) state 2

EMD-54291

Single-particle
3.0 Å
EMD-54291
3D View Gallery
Deposition: 09/07/2025
Map released: 13/05/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human TRPC5 in complex with (-) englerin A, partial occupancy (2EA:2LIP stoichiometry) state 2
Fitted models: 9rvv

Deposition Authors: Porav AS, Bon RS, Muench S
(-)-Englerin A binding to human TRPC5 exposes an aromatic interaction network in channel activation.
Porav SA, Ptakova A, Bauer CC, Hammond KLR, Beech DJ, Vlachova V, Muench SP, Bon RS
(2026) Nat Commun , 17
PUBMED: 42056091
DOI: doi:10.1038/s41467-026-71840-y
ISSN: 2041-1723