EMD-54194

Single-particle
11.77 Å
EMD-54194
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Deposition: 27/06/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54194
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ZZ1-SO2H-induced assembly of the YPEL5-CTLH E3 ligase and BRD4(BD1) neosubstrate

EMD-54194

Single-particle
11.77 Å
EMD-54194
3D View Gallery
Deposition: 27/06/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ZZ1-SO2H-induced complex of YPEL5-CTLH E3 ligase and the first bromodomain (BD1) of BRD4

Deposition Authors: Chrustowicz J , Schulman BA

Molecular Glue Prodrug Discovery Enabled by Targeted Degron Display
Zhuang Z, Woong Sub B, Chrustowicz J , Kozicka Z, Hinshaw SM, Li VL, Donovan KA, Sepic S, You I, Slabicki M, Fischer ES, Ebert BL, Schulman BA , Gray NS
To Be Published