EMD-54070

Single-particle
4.85 Å
EMD-54070
3D View Gallery
Deposition: 19/06/2025
Map released: 10/12/2025
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54070
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CryoEM reconstruction of integrase filament at the lumen of native HIV-1 cores (box size 47.3 nm)

EMD-54070

Single-particle
4.85 Å
EMD-54070
3D View Gallery
Deposition: 19/06/2025
Map released: 10/12/2025
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human immunodeficiency virus 1
Sample: Human immunodeficiency virus 1

Deposition Authors: Cherepanov P, Singer MR, Hope J, Zhang P
Integrase anchors viral RNA to the HIV-1 capsid interior.
Singer MR, Li Z, Rey JS, Hope J, Chenavier F, Cook NJ, Punch E, Smith J, Zhou Z, Maslen S, Masino L, Nans A, Skehel M, Taylor IA, Zanetti G, Zhang P, Perilla JR, Engelman AN, Cherepanov P
(2026) Nature , 652 , 1068 - 1075
PUBMED: 41708858
DOI: doi:10.1038/s41586-026-10154-x
ISSN: 1476-4687
ASTM: NATUAS