EMD-54031

Single-particle
3.1 Å
EMD-54031
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Deposition: 16/06/2025
Map released: 18/03/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54031
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9rl5 summary report (pdf.gz) Map and 9rl5 FULL report (pdf.gz)
EMICSS annotations (xml)

a5b3 GABAAR bound to Topiramate, GABA, and Mb25 in a desensitized state in saposin nanodiscs

EMD-54031

Single-particle
3.1 Å
EMD-54031
3D View Gallery
Deposition: 16/06/2025
Map released: 18/03/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Escherichia coli
Sample: human a5b3 GABAA receptor bound to topiramate, GABA, and Megabody 25
Fitted models: 9rl5

Deposition Authors: Cowgirl J, Lindahl E, Howard RJ

Structural basis for activation and potentiation in a human a5b3 GABAA receptor
Cowgill J, Howard RJ, Lindahl E
To Be Published