EMD-54023

Single-particle
8.0 Å
EMD-54023
3D View Gallery
Deposition: 15/06/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54023

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9rkw summary report (pdf.gz) Map-9rkw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Insulin receptor ectodomain in complex with s661 insulin mimetic

EMD-54023

Single-particle
8.0 Å
EMD-54023
3D View Gallery
Deposition: 15/06/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Insulin receptor ecto-domain in complex with s661 insulin mimetic
Fitted models: 9rkw

Deposition Authors: Polak M, Novacek J, Jiracek J

Antagonistic insulin mimetics lock the insulin receptor in an alternative apo-state
Polak M, Pinkas M, Hernandez MSG, Fabre B, Lubos M, Zakova L, Grzybek M, Schaefer IB, Coskun U, Jiracek J, Novacek J
To Be Published