EMD-54006
Population B fibril generated from the Heterotypic interaction of Abeta40 and Medin.
EMD-54006
Helical reconstruction2.63 Å
Deposition: 11/06/2025Map released: 08/04/2026
Last modified: 08/04/2026
Sample Organism:
Homo sapiens
Sample: In vitro assembled, recombinantly purified Amyloid Beta 40 peptide in co-aggregation with synthetically produced Medin.
Fitted models: 9riv
Deposition Authors: Pradhan B
,
Kumar ST
,
Wagner J
,
Gallardo R,
Orlando G
,
Vleeschouwer MD
,
Madine J
,
Louros N
,
Neher J
,
Schymkowitz J
,
Rousseau F
Sample: In vitro assembled, recombinantly purified Amyloid Beta 40 peptide in co-aggregation with synthetically produced Medin.
Fitted models: 9riv
Deposition Authors: Pradhan B
,
Kumar ST
,
Wagner J
,
Gallardo R,
Orlando G
,
Vleeschouwer MD
,
Madine J
,
Louros N
,
Neher J
,
Schymkowitz J
,
Rousseau F
In Vitro Co-Aggregation with medin Induces an Abeta42-Like Polymorph of Abeta40 Fibrils.
Pradhan B
,
Kumar ST
,
Wagner J
,
Gallardo R,
Orlando G
,
Vleeschouwer MD
,
Madine J
,
Louros N
,
Neher J
,
Schymkowitz J
,
Rousseau F
To Be Published
,
Kumar ST
,
Wagner J
,
Gallardo R,
Orlando G
,
Vleeschouwer MD
,
Madine J
,
Louros N
,
Neher J
,
Schymkowitz J
,
Rousseau F
To Be Published
Grant Support:
- Research Foundation - Flanders (FWO): G0C3522N (Belgium)
- Research Foundation - Flanders (FWO): 12AWB24N (Belgium)
- National Institutes of Health/National Institute on Aging (NIH/NIA): R01AG079234 (United States)
