EMD-53973

Single-particle
3.7 Å
EMD-53973
3D View Gallery
Deposition: 09/06/2025
Map released: 13/05/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53973

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9rhm summary report (pdf.gz) Map-9rhm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Phospho-MCM double hexamer bound to Sld3-Sld7-Cdc45 on ARS1 DNA

EMD-53973

Single-particle
3.7 Å
EMD-53973
3D View Gallery
Deposition: 09/06/2025
Map released: 13/05/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: Phospho-DH bound by Sld3/7 and Cdc45 on replication origin
Fitted models: 9rhm

Deposition Authors: Puehringer T, Couves EC, Costa A
Structure of the pre-initiation complex explains CMGE biogenesis.
Puhringer T, Canal B, Palm G, Butryn A, Couves EC, Willhoft O, Lewis JS, Diffley JFX, Costa A
(2026) Nature
PUBMED: 42310460
DOI: doi:10.1038/s41586-026-10657-7
ISSN: 1476-4687
ASTM: NATUAS