Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-53506

Single-particle
3.2 Å
EMD-53506 Deposition: 26/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53506

Cryo-EM structure of human MATE1 in complex with MPP

EMD-53506

Single-particle
3.2 Å
EMD-53506 Deposition: 26/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human multidrug and toxin extrusion protein (MATE1) in complex with Fab and MPP
Fitted models: 9r1e

Deposition Authors: Romane K , Peteani G, Mukherjee S , Kowal J , Rossi L , Hou J , Kossiakoff A, Lemmin T , Locher KP
Structural basis of drug recognition by human MATE1 transporter.
Romane K , Peteani G, Mukherjee S , Kowal J , Rossi L , Hou J , Kossiakoff AA , Lemmin T , Locher KP
(2025) Nat Commun , 16 , 9444 - 9444
PUBMED: 41145429
DOI: doi:10.1038/s41467-025-64490-z
ISSN: 2041-1723