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EMD-53426
Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (C-term dimer interface focused refinement)
EMD-53426
Single-particle3.1 Å
Deposition: 15/04/2025Map released: 03/09/2025
Last modified: 22/10/2025
Sample Organism:
Homo sapiens
Sample: Human UBR4/KCMF1/CALM1 complex
Fitted models: 9qws
Deposition Authors: Grabarczyk DB
,
Clausen T
Sample: Human UBR4/KCMF1/CALM1 complex
Fitted models: 9qws
Deposition Authors: Grabarczyk DB
,
Clausen T
Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control.
Grabarczyk DB ,
Ehrmann JF ,
Murphy P,
Yang WS ,
Kurzbauer R,
Bell LE ,
Deszcz L ,
Neuhold J,
Schleiffer A ,
Shulkina A,
Lee J ,
Shin JS ,
Meinhart A ,
Versteeg GA ,
Zavodszky E ,
Song HK ,
Hegde RS ,
Clausen T
(2025) Science , 389 , 909 - 914
,
Ehrmann JF ,
Murphy P,
Yang WS ,
Kurzbauer R,
Bell LE ,
Deszcz L ,
Neuhold J,
Schleiffer A ,
Shulkina A,
Lee J ,
Shin JS ,
Meinhart A ,
Versteeg GA ,
Zavodszky E ,
Song HK ,
Hegde RS ,
Clausen T
(2025) Science , 389 , 909 - 914
Grant Support:
- Austrian Research Promotion Agency: 852936 (Austria)
- H2020 Marie Curie Actions of the European Commission: 847548 (European Union)