EMD-53425

Single-particle
7.7 Å
EMD-53425
3D View Gallery
Deposition: 15/04/2025
Map released: 17/09/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53425

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human UBR4 complex (ZZ-DZB deletion variant)

EMD-53425

Single-particle
7.7 Å
EMD-53425
3D View Gallery
Deposition: 15/04/2025
Map released: 17/09/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human UBR4 complex (ZZ-DZB deletion)

Deposition Authors: Grabarczyk DB , Clausen T
Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control.
Grabarczyk DB , Ehrmann JF , Murphy P, Yang WS , Kurzbauer R, Bell LE , Deszcz L , Neuhold J, Schleiffer A , Shulkina A, Lee J , Shin JS , Meinhart A , Versteeg GA , Zavodszky E , Song HK , Hegde RS , Clausen T
(2025) Science , 389 , 909 - 914
PUBMED: 40875847
DOI: doi:10.1126/science.adv9309
ISSN: 1095-9203
ASTM: SCIEAS