EMD-53392
human PAN2-PAN3 bound to a 90Ai/PABPC1 RNP
EMD-53392
Single-particle7.0 Å
Deposition: 11/04/2025Map released: 10/12/2025
Last modified: 10/12/2025
Sample Organism:
Homo sapiens
Sample: heterotrimeric PAN2-PAN3 mRNA deadenylase complex composed of the regulatory PAN3 homodimer bound to the catalytic PAN2 in complex with an inhibitory 90Ai/PABPC1 RNP
Deposition Authors: Albrecht JC
,
Reitinger T ,
Basquin J ,
Schuessler S ,
Schaefer IB ,
Conti E
Sample: heterotrimeric PAN2-PAN3 mRNA deadenylase complex composed of the regulatory PAN3 homodimer bound to the catalytic PAN2 in complex with an inhibitory 90Ai/PABPC1 RNP
Deposition Authors: Albrecht JC
,
Reitinger T ,
Basquin J ,
Schuessler S ,
Schaefer IB ,
Conti E
Mechanisms governing poly(A)-tail-length specificity of the human PAN2-PAN3 deadenylase complex.
Albrecht JC ,
Reitinger T ,
Basquin J ,
Schussler S,
Riggi M,
Schafer IB,
Conti E
(2025) Cell Rep , 44 , 116609 - 116609
,
Reitinger T ,
Basquin J ,
Schussler S,
Riggi M,
Schafer IB,
Conti E
(2025) Cell Rep , 44 , 116609 - 116609
Grant Support:
- European Research Council (ERC): 740329 (European Union)
- European Research Council (ERC): 101054447 (European Union)
- German Research Foundation (DFG): SFB1035 (Germany)
- Novo Nordisk Foundation: 31199 (Denmark)
- German Federal Ministry for Education and Research: DZD (Germany)