EMD-53355

Single-particle
2.28 Å
EMD-53355
3D View Gallery
Deposition: 09/04/2025
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53355
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9qtn summary report (pdf.gz) Map and 9qtn FULL report (pdf.gz)
EMICSS annotations (xml)

Human alpha7 nicotinic receptor in complex with the F1 nanobody

EMD-53355

Single-particle
2.28 Å
EMD-53355
3D View Gallery
Deposition: 09/04/2025
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Vicugna pacos
Sample: Human nicotinic acetylcholine receptor alpha7 in complex with Nanobody F1
Fitted models: 9qtn

Deposition Authors: Barilone N , Vangelatou M, Marouf FZ , Dejean de la Batie G, Ayme G , Lafaye P , Corringer P-J, Prevost MS
Discovery and mechanism of negative allosteric modulation of the alpha 7 nicotinic acetylcholine receptor by nanobodies.
Barilone N , Vangelatou M, Marouf FZ , Dejean de la Batie G, Li Q, Lafaye P , Ayme G , Corringer PJ, Prevost MS
(2026) PNAS , 123 , e2514734123 - e2514734123
PUBMED: 41576092
DOI: doi:10.1073/pnas.2514734123
ISSN: 1091-6490
ASTM: PNASA6