EMD-53320

Single-particle
3.1 Å
EMD-53320
3D View Gallery
Deposition: 03/04/2025
Map released: 24/09/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53320

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qrn summary report (pdf.gz) Map-9qrn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

DNA polymerase without DNA or inhibitor

EMD-53320

Single-particle
3.1 Å
EMD-53320
3D View Gallery
Deposition: 03/04/2025
Map released: 24/09/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Enterococcus faecium, Escherichia coli
Sample: DNA polymerase with DNA and inhibitor
Fitted models: 9qrn

Deposition Authors: Lamers MH , Urem M , Smits WK
A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens.
Urem M , Friggen AH, Musch N , Silverman MH , Swain CJ , Barbachyn MR, Mortin LI , Yu X, DeLuccia RJ , Lamers MH , Smits WK
(2025) Nat Commun , 16 , 9784 - 9784
PUBMED: 41198680
DOI: doi:10.1038/s41467-025-65324-8
ISSN: 2041-1723
Grant Support: