Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-53281

Single-particle
3.56 Å
EMD-53281
3D View Gallery
Deposition: 28/03/2025
Map released: 14/05/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53281
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9qpr summary report (pdf.gz) Map and 9qpr FULL report (pdf.gz)
EMICSS annotations (xml)

Single particle cryo-EM structure of the multidrug efflux pump MdtF from Escherichia coli

EMD-53281

Single-particle
3.56 Å
EMD-53281
3D View Gallery
Deposition: 28/03/2025
Map released: 14/05/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli K-12
Sample: Homotrimer of WT multidrug resistance protein MdtF in SMALP nanodisc
Fitted models: 9qpr

Deposition Authors: Lawrence R , Adams C, Sousa JS, Ahdash Z , Reading E
Molecular basis for multidrug efflux by an anaerobic RND transporter.
Lawrence R , Athar M , Uddin MR , Adams C, Sousa JS, Durrant O , Lellman S , Sutton L , Keevil CW , Patel N, Prosser C, McMillan D, Zgurskaya HI , Vargiu AV , Ahdash Z , Reading E
(2025) bioRxiv
PUBMED: 40236129
DOI: doi:10.1101/2025.04.04.646765
ISSN: 2692-8205