EMD-53249

Single-particle
2.91 Å
EMD-53249
3D View Gallery
Deposition: 25/03/2025
Map released: 21/05/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53249

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qnr summary report (pdf.gz) Map-9qnr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of TTYH3 in GDN after incubation with ApoE, map2

EMD-53249

Single-particle
2.91 Å
EMD-53249
3D View Gallery
Deposition: 25/03/2025
Map released: 21/05/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TTYH3 dimer purified in GDN
Fitted models: 9qnr

Deposition Authors: Sukalskaia A , Pugnetti A , Dutzler R , Plochberger B , Weber F , Karner A
Interactions between TTYH2 and APOE facilitate endosomal lipid transfer.
Sukalskaia A , Karner A , Pugnetti A , Weber F , Plochberger B , Dutzler R
(2025) Nature , 644 , 273 - 279
PUBMED: 40562935
DOI: doi:10.1038/s41586-025-09200-x
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: