Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-52978

Single-particle
3.3 Å
EMD-52978
3D View Gallery
Deposition: 28/02/2025
Map released: 16/07/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52978
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9qax summary report (pdf.gz) Map and 9qax FULL report (pdf.gz)
EMICSS annotations (xml)

The catalytic core with C2 symmetry of human telomerase dimer

EMD-52978

Single-particle
3.3 Å
EMD-52978
3D View Gallery
Deposition: 28/02/2025
Map released: 16/07/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The catalytic core with C2 symmetry of human telomerase dimer
Fitted models: 9qax

Deposition Authors: Balch S , Sekne Z , Franco-Echevarria E , Ludzia P , Kretsch RC , Sun W , Yu H , Ghanim GE , Sigurdur TR, Ding Y , Das R , Nguyen THD
Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Balch S , Sekne Z , Franco-Echevarria E , Ludzia P , Kretsch RC , Sun W , Yu H , Ghanim GE , Thorkelsson S , Ding Y , Das R , Nguyen THD
(2025) Science , 389 , eadr5817 - eadr5817
PUBMED: 40638752
DOI: doi:10.1126/science.adr5817
ISSN: 1095-9203
ASTM: SCIEAS