EMD-52972

Single-particle
2.81 Å
EMD-52972
3D View Gallery
Deposition: 27/02/2025
Map released: 25/06/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52972

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qa6 summary report (pdf.gz) Map-9qa6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Thomasclavelia ramosa IgA peptidase (IgAse) active site mutant (S32-N876)

EMD-52972

Single-particle
2.81 Å
EMD-52972
3D View Gallery
Deposition: 27/02/2025
Map released: 25/06/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Thomasclavelia ramosa
Sample: Monomeric IgA peptidase active site mutant - E540A including the N-terminal domain
Fitted models: 9qa6

Deposition Authors: Ramirez-Larrota JS , Eckhard U, Guerra P, Juyoux P, Gomis-Ruth FX
Biochemical and structural characterization of the human gut microbiome metallopeptidase IgAse provides insight into its unique specificity for the Fab' region of IgA1 and IgA2.
Ramirez-Larrota JS , Juyoux P, Guerra P, Eckhard U, Gomis-Ruth FX
(2025) PLoS Pathog , 21 , e1013292 - e1013292
PUBMED: 40627637
DOI: doi:10.1371/journal.ppat.1013292
ISSN: 1553-7374