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EMD-52966
HSV-2 prefusion glycoprotein B bound by Nb1_gbHSV
EMD-52966
Single-particle2.7 Å
Deposition: 26/02/2025Map released: 03/09/2025
Last modified: 22/10/2025
Sample Organism:
Human herpesvirus 2 strain 333,
Vicugna pacos
Sample: Herpes Simplex Virus 2 Glycoprotein B in complex with Nb1_gbHSV
Fitted models: 9q9s
Deposition Authors: Vollmer B
,
Mulvaney T ,
Ebel H ,
Nentwig J ,
Gruenewald K
Sample: Herpes Simplex Virus 2 Glycoprotein B in complex with Nb1_gbHSV
Fitted models: 9q9s
Deposition Authors: Vollmer B
,
Mulvaney T ,
Ebel H ,
Nentwig J ,
Gruenewald K
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2.
Vollmer B ,
Ebel H ,
Rees R,
Nentwig J ,
Mulvaney T ,
Schunemann J,
Krull J,
Topf M ,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
,
Ebel H ,
Rees R,
Nentwig J ,
Mulvaney T ,
Schunemann J,
Krull J,
Topf M ,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
Grant Support:
- German Research Foundation (DFG): 2771, 2887 (Germany)
- German Research Foundation (DFG): INST 152/772-1|152/774-1|152/776-1 FUGG (Germany)
- German Federal Ministry for Education and Research: ASPIRE (Germany)
- Wellcome Trust: 209250/Z/17/Z (United Kingdom)