Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-52963
HSV-1 prefusion glycoprotein B
EMD-52963
Single-particle2.64 Å
Deposition: 26/02/2025Map released: 03/09/2025
Last modified: 22/10/2025
Sample Organism:
Human alphaherpesvirus 1 strain 17
Sample: Human alphaherpesvirus 1 Glycoprotein B
Fitted models: 9q9l
Deposition Authors: Vollmer B
,
Mulvaney T
,
Ebel H
,
Nentwig J
,
Gruenewald K
Sample: Human alphaherpesvirus 1 Glycoprotein B
Fitted models: 9q9l
Deposition Authors: Vollmer B
,
Mulvaney T
,
Ebel H
,
Nentwig J
,
Gruenewald K
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2.
Vollmer B
,
Ebel H
,
Rees R,
Nentwig J
,
Mulvaney T
,
Schunemann J,
Krull J,
Topf M
,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
,
Ebel H
,
Rees R,
Nentwig J
,
Mulvaney T
,
Schunemann J,
Krull J,
Topf M
,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
Grant Support:
- German Research Foundation (DFG): INST 152/772-1, 152/774-1, 152/776-1 (Germany)
- German Federal Ministry for Education and Research: ASPIRE project (Germany)
- German Research Foundation (DFG): Research training groups 2771 & 2887 (Germany)
- Wellcome Trust: 209250/Z/17/Z (United Kingdom)
